Cicatricial pemphigoid with laryngeal involvement

Ocular involvement in anti-epiligrin cicatricial pemphigoid.

PURPOSE To report an anti-epiligrin cicatricial pemphigoid (AECP) patient with severe ocular involvement and to provide a practical approach to distinguishing AECP patients from those with other subepidermal blistering diseases. METHODS Techniques included direct and indirect immunofluorescence microscopy, Western blot and immunoprecipitation studies, as well as interdisciplinary examinations...

Multiple mucosal involvement in cicatricial pemphigoid.

Mucous membrane pemphigoid includes chronic autoimmune sub-epithelial blistering diseases that predominantly affect mucous membranes, with varying combinations of oral, ocular, cutaneous, genital, nasopharyngeal, oesophageal and laryngeal lesions. The case is reported of a man with multiple manifestations of mucous membrane pemphigoid. A 53-year-old male presented at our Department with a 4-yea...

Ocular Cicatricial Pemphigoid

CC (6/20/96): Red, itchy eyes, whitish discharge x 6 weeks HPI: A 74 year old retired policeman noticed red, itchy eyes associated with whitish discharge that worsened over the past six weeks. Two weeks later, the patient consulted his ophthalmologist, who treated him antibiotic eye drops without a favorable response. The patient did not respond to the antibiotic and states he was biopsied. He ...

Paraneoplastic mucous membrane pemphigoid with ocular and laryngeal involvement

A 73-year-old woman was treated 8 years previously for synchronous breast and uterine neoplasms. She presented with a severe sore throat, odynophagia, dysphonia, dyspnoea, ocular irritation and weight loss over the last 3 months. Physical examination revealed ulcerations in the oral cavity, posterior pharyngeal wall and supraglottic larynx, nasal crusting, bilateral conjunctivitis and three cut...

Laryngeal involvement in a patient with bullous pemphigoid.